Empty nest syndrome is a feeling of grief and loneliness parents or guardians may feel when their children leave home for the first time, such as to live on their own or to attend a college or university. It is not a clinical condition. Since a young adult moving out from his or her parents’ house is generally a normal and healthy event, the symptoms of empty nest syndrome often go unrecognized. This can result in depression and a loss of purpose for parents, since the departure of their children from “the nest” leads to adjustments in parents’ lives. Empty nest syndrome is especially common in full-time mothers.